BDBM476339 US10874687, Sofosbuvir

SMILES CC(C)OC(=O)[C@H](C)N[P@](=O)(OCC1O[C@@H](n2ccc(=O)[nH]c2=O)[C@](C)(F)[C@@H]1O)Oc1ccccc1

InChI Key InChIKey=TTZHDVOVKQGIBA-UHFFFAOYSA-N

Data  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 476339   

TargetReplicase polyprotein 1ab(HCoV-229E)
Atea Pharmaceuticals

US Patent
LigandPNGBDBM476339(US10874687, Sofosbuvir)
Affinity DataEC50: >1.00E+5nMAssay Description:Compound activity against coronavirus was based on inhibition of virus induced cytopathogenicity acutely infected with a multiplicity of infection (m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2021
Entry Details
Go to US Patent

TargetReplicase polyprotein 1ab(HCoV-229E)
Atea Pharmaceuticals

US Patent
LigandPNGBDBM476339(US10874687, Sofosbuvir)
Affinity DataEC50: >1.00E+5nMAssay Description:Compound activity against coronavirus was based on inhibition of virus induced cytopathogenicity acutely infected with a multiplicity of infection (m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2021
Entry Details
Go to US Patent

TargetReplicase polyprotein 1ab(HCoV-OC43)
Atea Pharmaceuticals

US Patent
LigandPNGBDBM476339(US10874687, Sofosbuvir)
Affinity DataEC50: >1.00E+5nMAssay Description:Compound activity against coronavirus was based on inhibition of virus induced cytopathogenicity acutely infected with a multiplicity of infection (m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2021
Entry Details
Go to US Patent

TargetReplicase polyprotein 1ab(HCoV-OC43)
Atea Pharmaceuticals

US Patent
LigandPNGBDBM476339(US10874687, Sofosbuvir)
Affinity DataEC50: >1.00E+5nMAssay Description:Compound activity against coronavirus was based on inhibition of virus induced cytopathogenicity acutely infected with a multiplicity of infection (m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2021
Entry Details
Go to US Patent