BDBM476272 US10874640, Compound 34::US20230270719, Compound 34

SMILES CNC(=O)C1(CC(F)(F)C1)NC(=O)C(=O)c1c(C)c(C(=O)Nc2ccc(F)c(Cl)c2)n2C[C@@H]3C[C@@H]3c12

InChI Key InChIKey=RIFWFIFVSKLFAT-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 476272   

TargetCapsid protein(HBV-C)
Gilead Sciences

US Patent
LigandPNGBDBM476272(US10874640, Compound 34 | US20230270719, Compound ...)
Affinity DataEC50:  202nMAssay Description:A HepG2 cell line overexpressing the HBV virus attachment receptor sodium-taurocholate cotransporting polypeptide (NTCP) was grown to confluency in D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2021
Entry Details
Go to US Patent

TargetSodium/bile acid cotransporter(Human)
Gilead Sciences

US Patent
LigandPNGBDBM476272(US10874640, Compound 34 | US20230270719, Compound ...)
Affinity DataEC50:  202nMAssay Description:A HepG2 cell line overexpressing the HBV virus attachment receptor sodium-taurocholate cotransporting polypeptide (NTCP) was grown to confluency in D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2023
Entry Details
Go to US Patent