BDBM476259 N-(3-chloro-4-fluorophenyl)-6-methyl-7-(2-((3-methyl-1,1-dioxidothietan-3-yl)amino)-2-oxoacetyl)-2,3-dihydro-1H-pyrrolizine-5-carboxamide (21)::US10874640, Compound 21::US20230270719, Compound 21

SMILES Cc1c(C(=O)C(=O)NC2(C)CS(=O)(=O)C2)c2CCCn2c1C(=O)Nc1ccc(F)c(Cl)c1

InChI Key InChIKey=SDJHYHWSPXKRPO-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 476259   

TargetCapsid protein(HBV-C)
Gilead Sciences

US Patent
LigandPNGBDBM476259(N-(3-chloro-4-fluorophenyl)-6-methyl-7-(2-((3-meth...)
Affinity DataEC50:  20.1nMAssay Description:A HepG2 cell line overexpressing the HBV virus attachment receptor sodium-taurocholate cotransporting polypeptide (NTCP) was grown to confluency in D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2021
Entry Details
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TargetSodium/bile acid cotransporter(Human)
Gilead Sciences

US Patent
LigandPNGBDBM476259(N-(3-chloro-4-fluorophenyl)-6-methyl-7-(2-((3-meth...)
Affinity DataEC50:  20.1nMAssay Description:A HepG2 cell line overexpressing the HBV virus attachment receptor sodium-taurocholate cotransporting polypeptide (NTCP) was grown to confluency in D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2023
Entry Details
Go to US Patent