BDBM476243 (1aR,6aR)—N-(3-chloro-4-fluorophenyl)-5-(2-((3,3-difluoro-1-(methylcarbamoyl)cyclobutyl)amino)-2-oxoacetyl)-4-methyl-1,1a,6,6a-tetrahydrocyclopropa[b]pyrrolizine-3-carboxamide (5)::US10874640, Compound 5

SMILES CNC(=O)C1(CC(F)(F)C1)NC(=O)C(=O)c1c(C)c(C(=O)OC)n2[C@@H]3C[C@@H]3Cc12

InChI Key InChIKey=SBSNYGNJKJIYTI-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 476243   

TargetCapsid protein(HBV-C)
Gilead Sciences

US Patent
LigandPNGBDBM476243((1aR,6aR)—N-(3-chloro-4-fluorophenyl)-5-(2-((...)
Affinity DataEC50:  8.80nMAssay Description:A HepG2 cell line overexpressing the HBV virus attachment receptor sodium-taurocholate cotransporting polypeptide (NTCP) was grown to confluency in D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2021
Entry Details
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