BDBM476237 US10874634, Cmpd No. 19::US11364220, Compound 19

SMILES CC(C)C(C(O)=O)c1ccc(NS(=O)(=O)c2cc3c(cc2C)C(C)(C)CCC3(C)C)cc1

InChI Key InChIKey=NJFQFQKDVLAUCN-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 476237   

TargetCytochrome P450 26A1(Human)
Queens University At Kingston

US Patent
LigandPNGBDBM476237(US10874634, Cmpd No. 19 | US11364220, Compound 19)
Affinity DataIC50: 741nMAssay Description:CYP26A1 or CYP26B1 stably transfected HeLa cells were maintained in Minimum Essential Medium (MEM) containing 10% fetal bovine serum (FBS) and 100 &#...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2021
Entry Details
Go to US Patent

TargetCytochrome P450 26B1(Human)
Queens University At Kingston

US Patent
LigandPNGBDBM476237(US10874634, Cmpd No. 19 | US11364220, Compound 19)
Affinity DataIC50: 1.00E+5nMAssay Description:CYP26A1 or CYP26B1 stably transfected HeLa cells were maintained in Minimum Essential Medium (MEM) containing 10% fetal bovine serum (FBS) and 100 &#...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2021
Entry Details
Go to US Patent

TargetCytochrome P450 26A1(Human)
Queens University At Kingston

US Patent
LigandPNGBDBM476237(US10874634, Cmpd No. 19 | US11364220, Compound 19)
Affinity DataIC50: 741nMAssay Description:This retinoid activity assay measures the ability of test compounds to induce expression of a transiently transfected RA sensitive reporter construct...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
Go to US Patent

TargetCytochrome P450 26B1(Human)
Queens University At Kingston

US Patent
LigandPNGBDBM476237(US10874634, Cmpd No. 19 | US11364220, Compound 19)
Affinity DataIC50: 1.00E+5nMAssay Description:This retinoid activity assay measures the ability of test compounds to induce expression of a transiently transfected RA sensitive reporter construct...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
Go to US Patent