BDBM476105 US10865208, Compound I-160::{(2R,3S,5R)-5-[4-amino-3-(2,3-dihydro-1H-inden-5-ylsulfanyl)-1H-pyrazolo[3,4- d]pyrimidin-1-yl]-3-hydroxytetrahydrofuran-2-yl}methyl sulfamate
SMILES Nc1ncnc2n(nc(Sc3ccc4CCCc4c3)c12)[C@H]1C[C@H](O)[C@@H](COS(N)(=O)=O)O1
InChI Key InChIKey=RJMHDSDUKCLGLF-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 476105
Affinity DataIC50: 75nMAssay Description:The total volume of the ATG7 enzymatic assay is 50 μL and contains 50 mM HEPES Hemisodium (pH 7.5), 0.05% BSA, 0.01% Tween-20, 25 mM NaCl, 5 mM ...More data for this Ligand-Target Pair
Affinity DataIC50: 66nMAssay Description:Inhibition of recombinant His-tagged human ATG7 incubated for 105 mins in presence of GST-tagged ATG3 and Flag-tagged Gabarap and measured after 2 hr...More data for this Ligand-Target Pair