BDBM475677 5-(1-hydroxy-2-(2-(4-methyl-1H- imidazol-1-yl)-7,8-dihydropyrido[4,3-d] pyrimidin-6(5H)-yl)ethyl)-4-methyl isobenzofuran-1(3H)-one (Enantiomer-I)::US10851108, Example 58-I

SMILES Cc1cn(cn1)-c1ncc2CN(CC(O)c3ccc4C(=O)OCc4c3C)CCc2n1

InChI Key InChIKey=INVMSLQVRSOFGL-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 475677   

TargetATP-sensitive inward rectifier potassium channel 1(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM475677(5-(1-hydroxy-2-(2-(4-methyl-1H- imidazol-1-yl)-7,8...)
Affinity DataIC50: 13nMAssay Description:The coverslip plated with cells was placed in the experiment chamber perfused with bath solution composed of (in mM): 135 NaCl, 5 KCl, 2 CaCl2, 1 MgC...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/12/2021
Entry Details
US Patent