BDBM475675 5-(2-(2-(1H-imidazo[4,5-b]pyridin-1- yl)-7,8-dihydropyrido[4,3-d]pyrimidin- 6(5H)-yl)-1-hydroxyethyl)-4- methylisobenzofuran-1(3H)-one (Enantiomer-I)::US10851108, Example 53-I

SMILES Cc1c2COC(=O)c2ccc1C(O)CN1CCc2nc(ncc2C1)-n1cnc2ncccc12

InChI Key InChIKey=FTPBTOYQLJQZNK-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 475675   

TargetATP-sensitive inward rectifier potassium channel 1(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM475675(5-(2-(2-(1H-imidazo[4,5-b]pyridin-1- yl)-7,8-dihyd...)
Affinity DataIC50: 87nMAssay Description:The coverslip plated with cells was placed in the experiment chamber perfused with bath solution composed of (in mM): 135 NaCl, 5 KCl, 2 CaCl2, 1 MgC...More data for this Ligand-Target Pair
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Date in BDB:
7/12/2021
Entry Details
US Patent