BDBM475672 2-fluoro-4-((2-((1-oxo-1,3-dihydroisobenzofuran-5-yl)methyl)-1,2,3,4-tetrahydroisoquinolin-6-yl)amino)benzonitrile::US10851108, Example 4

SMILES Fc1cc(Nc2ccc3CN(Cc4ccc5C(=O)OCc5c4)CCc3c2)ccc1C#N

InChI Key InChIKey=AGLNCQJYRXKZQZ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 475672   

TargetATP-sensitive inward rectifier potassium channel 1(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM475672(2-fluoro-4-((2-((1-oxo-1,3-dihydroisobenzofuran-5-...)
Affinity DataIC50: 31nMAssay Description:The coverslip plated with cells was placed in the experiment chamber perfused with bath solution composed of (in mM): 135 NaCl, 5 KCl, 2 CaCl2, 1 MgC...More data for this Ligand-Target Pair
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Date in BDB:
7/12/2021
Entry Details
US Patent