BDBM475195 US10851082, NUCC-0125589

SMILES C(Cc1ccncc1)Nc1nccc(n1)-c1cn[nH]c1

InChI Key InChIKey=SVNMPYRXBYGCHD-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 475195   

TargetMAP kinase-interacting serine/threonine-protein kinase 1(Human)
Northwestern University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 475195BDBM475195(US10851082, NUCC-0125589)
Affinity DataIC50: 3.40E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details PubMed
TargetMAP kinase-interacting serine/threonine-protein kinase 2(Human)
Northwestern University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 475195BDBM475195(US10851082, NUCC-0125589)
Affinity DataIC50: 5.60E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details PubMed
TargetMAP kinase-interacting serine/threonine-protein kinase 1(Human)
Northwestern University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 475195BDBM475195(US10851082, NUCC-0125589)
Affinity DataIC50: 1.30E+4nMAssay Description:The synthesized compounds then were tested for inhibition of the kinase activity (IC50) of Mnk1 and/or Mnk2 using the ADP monitoring assay for kinase...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/12/2021
Entry Details
US Patent