BDBM475039 US10849901, Compound 89::US10953012, Example 34

SMILES O=c1cc(Cc2ccccc2)[nH]c2c(c(nn12)-c1ccccc1)-c1ccccc1

InChI Key InChIKey=BLVVIFDPFZHYLP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 475039   

TargetADP-ribosylation factor 6(Human)
Navigen

US Patent
LigandPNGBDBM475039(US10849901, Compound 89 | US10953012, Example 34)
Affinity DataIC50: 7nMAssay Description:The primary biochemical assay uses a fluorometric assay for monitoring the replacement of bound nucleotide with a fluorogenic GTP derivative bearing ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/12/2021
Entry Details
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LigandPNGBDBM475039(US10849901, Compound 89 | US10953012, Example 34)
Affinity DataIC50: 1.00E+4nMAssay Description:Table 1: One assay for purified hPASK activity utilizes the Kinase-Glo Luminescent Kinase Assay (Promega), which quantifies the amount of ATP remaini...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2021
Entry Details
Go to US Patent