BDBM474594 US10849883, Compound 23b::US11559515, Compound 23b

SMILES C[C@H](NC(=O)Cn1nc(C(N)=O)c2ccccc12)C(=O)NCc1cccc(Cl)c1

InChI Key InChIKey=FYBDUBPGCVGPKG-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 474594   

TargetComplement factor D(Human)
Biocryst Pharmaceuticals

US Patent
LigandPNGBDBM474594(US10849883, Compound 23b | US11559515, Compound 23...)
Affinity DataIC50: 1.00E+3nMAssay Description:An established esterolytic assay for the measurement of Factor D activity and inhibition of Factor D activity was used (Kam, C. M.; McRae, B. J.; Har...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
US Patent

TargetComplement factor D(Human)
Biocryst Pharmaceuticals

US Patent
LigandPNGBDBM474594(US10849883, Compound 23b | US11559515, Compound 23...)
Affinity DataIC50: 1.00E+4nMAssay Description:An established esterolytic assay for the measurement of Factor D activity and inhibition of Factor D activity was used (Kam, C. M.; McRae, B. J.; Har...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/12/2021
Entry Details
US Patent