BDBM474430 US10858373, Example 28

SMILES FC(F)(F)C(OC(=O)N1CCC2(CC1)CN(CCO2)S(=O)(=O)CC1CCCCO1)C(F)(F)F

InChI Key InChIKey=VZQPSERQZWDYGE-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 474430   

TargetMonoglyceride lipase(Human)
Pfizer

US Patent
LigandPNGBDBM474430(US10858373, Example 28)
Affinity DataIC50: 10.3nMAssay Description:Assessment of MAGL inhibition utilizes human recombinant Monoacylglycerol Lipase and the fluorogenic substrate 7-hydroxycoumarinyl arachidonate (7-HC...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2021
Entry Details
Go to US Patent

TargetMonoglyceride lipase(Human)
Pfizer

US Patent
LigandPNGBDBM474430(US10858373, Example 28)
Affinity DataIC50: 2.22nMAssay Description:T = 30 minutes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2021
Entry Details
Go to US Patent