BDBM474361 (S)-6-benzhydryl-11-hydroxy-3-(1H-pyrazol- 4-yl)-5,6-dihydro-10H-imidazo[1,2- a]pyrido[2,1-c]pyrazin-10-one::US10858366, Example 52::US11453677, Example 52

SMILES Oc1c2-c3ncc(-c4cn[nH]c4)n3C[C@H](C(c3ccccc3)c3ccccc3)n2ccc1=O

InChI Key InChIKey=UXDGFVPFWODPIX-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 474361   

TargetPolymerase acidic protein(Influenza A virus (strain A/Victoria/3/1975 H3N2))
Novartis

US Patent
LigandPNGBDBM474361(US10858366, Example 52 | (S)-6-benzhydryl-11-hydro...)
Affinity DataIC50: 8nMAssay Description:Compounds were dissolved and serially diluted in 100% DMSO then 0.5 μl was transferred to 384-well plates. 50 nM truncated Influenza A/victoria/...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2021
Entry Details
Go to US Patent

TargetPolymerase acidic protein(Influenza A virus (strain A/Victoria/3/1975 H3N2))
Novartis

US Patent
LigandPNGBDBM474361(US10858366, Example 52 | (S)-6-benzhydryl-11-hydro...)
Affinity DataIC50: 8nMAssay Description:Compounds were dissolved and serially diluted in 100% DMSO then 0.5 μl was transferred to 384-well plates. 50 nM truncated Influenza A/victoria/...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2022
Entry Details
Go to US Patent