BDBM474335 (S)-7-(4-fluorophenyl)-8-(3-methylimidazo[1,2-a] pyridin-6-yl)-2-((l-methylpyrrolidin-2-yl)methyl)- [1,2,4]triazolo[1,5-c]pyrimidin-5-amine::US10858365, Compound 122
SMILES CN1CCC[C@H]1Cc1nc2c(-c3ccc4ncc(C)n4c3)c(nc(N)n2n1)-c1ccc(F)cc1
InChI Key InChIKey=BFJGLGUWQKURET-UHFFFAOYSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 474335
Affinity DataIC50: 0.300nMAssay Description:The compounds at different concentrations were incubate with hA1 membrane (from PerkinElmer) and [3H]-8-Cyclopentyl-1,3-dipropylxanthine (DPCPX) for ...More data for this Ligand-Target Pair
Affinity DataIC50: 93.5nMAssay Description:hADORA1/CHO (hA1 expressing) cells (Genscript) were plated at 1×104 cells/well into 384-well polystyrene plates one day before starting the experimen...More data for this Ligand-Target Pair
Affinity DataIC50: 2.60nMAssay Description:hADORA1/CHO (hA1 expressing) cells (Genscript) were plated at 1×104 cells/well into 384-well polystyrene plates one day before starting the experimen...More data for this Ligand-Target Pair
Affinity DataIC50: 67.7nMAssay Description:hADORA1/CHO (hA1 expressing) cells (Genscript) were plated at 1×104 cells/well into 384-well polystyrene plates one day before starting the experimen...More data for this Ligand-Target Pair