BDBM474278 5-(5-amino-2-(2,6-difluorobenzyl)-7-(4-fluoroph enyl)-[l,2,4]triazolo[1,5-c]pyrimidin-8-yl)-1- (1,1-dioxidothietan-3-yl)pyridin-2(lH)-one::US10858365, Compound 60
SMILES Nc1nc(-c2ccc(F)cc2)c(-c2ccc(=O)n(c2)C2CS(=O)(=O)C2)c2nc(Cc3c(F)cccc3F)nn12
InChI Key InChIKey=SALOGHGNVNNDIX-UHFFFAOYSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 474278
Affinity DataIC50: 56nMAssay Description:The compounds at different concentrations were incubate with hA1 membrane (from PerkinElmer) and [3H]-8-Cyclopentyl-1,3-dipropylxanthine (DPCPX) for ...More data for this Ligand-Target Pair
Affinity DataIC50: 3.30E+3nMAssay Description:hADORA1/CHO (hA1 expressing) cells (Genscript) were plated at 1×104 cells/well into 384-well polystyrene plates one day before starting the experimen...More data for this Ligand-Target Pair
Affinity DataIC50: 16nMAssay Description:hADORA1/CHO (hA1 expressing) cells (Genscript) were plated at 1×104 cells/well into 384-well polystyrene plates one day before starting the experimen...More data for this Ligand-Target Pair
Affinity DataIC50: 40nMAssay Description:hADORA1/CHO (hA1 expressing) cells (Genscript) were plated at 1×104 cells/well into 384-well polystyrene plates one day before starting the experimen...More data for this Ligand-Target Pair