BDBM474258 5-[5-amino-7-(4-fluorophenyl)-2-[(3-fluoropyrid in-2-yl)methyl]-[1,2,4]triazolo[1,5-c]pyrimidin-8- yl]-l-[(3S)-oxolan-3-yl]-1,2-dihydropyridin-2-one::US10858365, Compound 23
SMILES Nc1nc(-c2ccc(F)cc2)c(-c2ccc(=O)n(c2)C2CCOC2)c2nc(Cc3c(F)cccc3F)nn12
InChI Key InChIKey=CWSYBLKOVQMKOU-UHFFFAOYSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 474258
Affinity DataIC50: 7.70nMAssay Description:The compounds at different concentrations were incubate with hA1 membrane (from PerkinElmer) and [3H]-8-Cyclopentyl-1,3-dipropylxanthine (DPCPX) for ...More data for this Ligand-Target Pair
Affinity DataIC50: 2.06E+3nMAssay Description:hADORA1/CHO (hA1 expressing) cells (Genscript) were plated at 1×104 cells/well into 384-well polystyrene plates one day before starting the experimen...More data for this Ligand-Target Pair
Affinity DataIC50: 2.90nMAssay Description:hADORA1/CHO (hA1 expressing) cells (Genscript) were plated at 1×104 cells/well into 384-well polystyrene plates one day before starting the experimen...More data for this Ligand-Target Pair
Affinity DataIC50: 26nMAssay Description:hADORA1/CHO (hA1 expressing) cells (Genscript) were plated at 1×104 cells/well into 384-well polystyrene plates one day before starting the experimen...More data for this Ligand-Target Pair