BDBM474101 Compound 8::US10858359, Example 8

SMILES CC(C)(C)[S@@](=O)N[C@@H]1COCC11CCN(CC1)c1cnc(Sc2cccc3NC(=O)C(F)(F)c23)c(N)n1

InChI Key InChIKey=QJBJZPKOHGGGHD-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 474101   

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Jacobio Pharmaceuticals

US Patent
LigandPNGBDBM474101(Compound 8 | US10858359, Example 8)
Affinity DataIC50: 21.4nMAssay Description:IC50 values were estimated using 6,8-difluoro-4-methylumbelliferyl phosphate (DiFMUP) as a substrate, SHP2 samples (diluted to 0.5 nM in reaction buf...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2021
Entry Details
US Patent