BDBM474087 Compound 7::US10858359, Example 7

SMILES CC(=O)N1CC(F)(F)c2c1cccc2Sc1ncc(nc1N)N1CCC2(COC[C@H]2N[S@](=O)C(C)(C)C)CC1

InChI Key InChIKey=PWAVEVXLJIOPSX-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 474087   

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Jacobio Pharmaceuticals

US Patent
LigandPNGBDBM474087(Compound 7 | US10858359, Example 7)
Affinity DataIC50: 25.8nMAssay Description:IC50 values were estimated using 6,8-difluoro-4-methylumbelliferyl phosphate (DiFMUP) as a substrate, SHP2 samples (diluted to 0.5 nM in reaction buf...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2021
Entry Details
US Patent