BDBM474027 N-(4-Methyl-5-{7-(methylsulfamoyl)-1-oxo-2-[(2S)-1,1,1- trifluoropropan-2-yl]-2,3-dihydro-1H-isoindol-5-yl}-1,3-thiazol-2- yl)acetamide::US10858355, Example 35

SMILES CNS(=O)(=O)c1cc(cc2CN([C@@H](C)C(F)(F)F)C(=O)c12)-c1sc(NC(C)=O)nc1C

InChI Key InChIKey=NJTBXYWHSOIWSV-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 474027   

LigandPNGBDBM474027(N-(4-Methyl-5-{7-(methylsulfamoyl)-1-oxo-2-[(2S)-1...)
Affinity DataIC50: 1nMAssay Description:The activity of recombinant human PI3Kγ (aa144-1102)-6His was determined by measuring the ADP level after phosphorylation of DiC8-PIP2 using a c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2021
Entry Details
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