BDBM474025 N-(5-{2-[(2S)-3,3-Dimethylbutan-2-yl]-7-(methylsulfamoyl)-1-oxo-2,3- dihydro-1H-isoindol-5-yl}-4-methyl-1,3-thiazol-2-yl)acetamide::US10858355, Example 33

SMILES CNS(=O)(=O)c1cc(cc2CN([C@@H](C)C(C)(C)C)C(=O)c12)-c1sc(NC(C)=O)nc1C

InChI Key InChIKey=OFCXXWXNDOBWNJ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 474025   

LigandPNGBDBM474025(N-(5-{2-[(2S)-3,3-Dimethylbutan-2-yl]-7-(methylsul...)
Affinity DataIC50: 1.58nMAssay Description:The activity of recombinant human PI3Kγ (aa144-1102)-6His was determined by measuring the ADP level after phosphorylation of DiC8-PIP2 using a c...More data for this Ligand-Target Pair
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Date in BDB:
7/11/2021
Entry Details
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