BDBM474021 N-[5-(2-[(1S)-1-Cyclopropylethyl]-7-{[(1,3-dimethyl-1H-pyrazol-4- yl)sulfonyl]amino}-1-oxo-2,3-dihydro-1H-isoindol-5-yl)-4-methyl-1,3- thiazol-2-yl]acetamide::US10858355, Example 29

SMILES C[C@@H](C1CC1)N1Cc2cc(cc(NS(=O)(=O)c3cn(C)nc3C)c2C1=O)-c1sc(NC(C)=O)nc1C

InChI Key InChIKey=WAZBHQMUCRGFMW-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 474021   

LigandPNGBDBM474021(N-[5-(2-[(1S)-1-Cyclopropylethyl]-7-{[(1,3-dimethy...)
Affinity DataIC50: 1.26nMAssay Description:The activity of recombinant human PI3Kγ (aa144-1102)-6His was determined by measuring the ADP level after phosphorylation of DiC8-PIP2 using a c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2021
Entry Details
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