BDBM474011 N-(5-{2-[(1S)-1-Cyclopropylethyl]-7-({[1-(fluoromethyl)cyclo- propyl]methyl}sulfamoyl)-1-oxo-2,3-dihydro-1H-isoindol-5-yl}-4- methyl-1,3-thiazol-2-yl)acetamide::US10858355, Example 19

SMILES C[C@@H](C1CC1)N1Cc2cc(cc(c2C1=O)S(=O)(=O)NCC1(CCF)CC1)-c1sc(NC(C)=O)nc1C

InChI Key InChIKey=KLBWDODQEVMJRQ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 474011   

LigandPNGBDBM474011(N-(5-{2-[(1S)-1-Cyclopropylethyl]-7-({[1-(fluorome...)
Affinity DataIC50: 0.398nMAssay Description:The activity of recombinant human PI3Kγ (aa144-1102)-6His was determined by measuring the ADP level after phosphorylation of DiC8-PIP2 using a c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2021
Entry Details
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