BDBM47396 (5-hydroxynaphthalen-1-yl) benzoate::(5-oxidanylnaphthalen-1-yl) benzoate::Benzoic acid 5-hydroxy-naphthalen-1-yl ester::MLS000030944::SMR000009914::benzoic acid (5-hydroxy-1-naphthalenyl) ester::benzoic acid (5-hydroxy-1-naphthyl) ester::cid_646429

SMILES Oc1cccc2c(OC(=O)c3ccccc3)cccc12

InChI Key InChIKey=TWYZJDASIMIAPK-UHFFFAOYSA-N

Data  3 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 47396   

TargetTyrosine-protein kinase JAK2(Human)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM47396(cid_646429 | (5-oxidanylnaphthalen-1-yl) benzoate ...)
Affinity DataIC50: 6.51E+3nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Center Affiliation: The Scripps Research Institute (TS...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2011
Entry Details
PCBioAssay
TargetStreptokinase A(Streptococcus pyogenes M1 GAS)
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM47396(cid_646429 | (5-oxidanylnaphthalen-1-yl) benzoate ...)
Affinity DataEC50:  6.37E+4nMAssay Description:Keywords: Group A streptococcus, GAS, streptokinase, expression, virulence, inhibition, dose response, EC50 Assay Overview: The goal of this assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/8/2011
Entry Details
PCBioAssay
TargetMitochondrial import inner membrane translocase subunit TIM10(Baker's yeast)
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM47396(cid_646429 | (5-oxidanylnaphthalen-1-yl) benzoate ...)
Affinity DataIC50: 4.84E+3nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute(SBMRI, San Diego, CA...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/3/2011
Entry Details
PCBioAssay
TargetEstrogen receptor(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM47396(cid_646429 | (5-oxidanylnaphthalen-1-yl) benzoate ...)
Affinity DataIC50: 2.23E+3nMAssay Description:Antagonist activity at ERalpha receptor LBD expressed in yeast AH109 cells assessed as inhibition of interaction with SRC1 after 24 hrs by alpha-gala...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetEstrogen receptor beta(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM47396(cid_646429 | (5-oxidanylnaphthalen-1-yl) benzoate ...)
Affinity DataEC50:  1.46E+3nMAssay Description:Agonist activity at ERbeta receptor LBD expressed in yeast AH109 cells assessed as interaction with SRC1 after 24 hrs by alpha-galactosidase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed