BDBM473614 US10844062, Example 50

SMILES Fc1ccc(NC(=O)c2cccc(c2)C(F)(F)F)cc1Nc1ncccc1-c1ncnc2[nH]cnc12

InChI Key InChIKey=WZXOYJFOAOEMJX-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 473614   

TargetVascular endothelial growth factor receptor 2(Human)
Incheon University Industry Academic Cooperation Foundation

US Patent
LigandPNGBDBM473614(US10844062, Example 50)
Affinity DataIC50: 90nMAssay Description:The inhibitory activities of the compounds of the present invention against VEGFR-2 tyrosine kinase were analyzed using ADP-Glo kinase assay kit comm...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2021
Entry Details
Go to US Patent