BDBM473605 US10844062, Example 41

SMILES CC(C)(C#N)c1cc(ccc1Cl)C(=O)Nc1ccc(F)c(Nc2ncccc2-c2ncnc3[nH]cnc23)c1F

InChI Key InChIKey=GZRLDTHKIGBGQM-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 473605   

TargetVascular endothelial growth factor receptor 2(Human)
Incheon University Industry Academic Cooperation Foundation

US Patent
LigandPNGBDBM473605(US10844062, Example 41)
Affinity DataIC50: 82nMAssay Description:The inhibitory activities of the compounds of the present invention against VEGFR-2 tyrosine kinase were analyzed using ADP-Glo kinase assay kit comm...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2021
Entry Details
Go to US Patent