BDBM473069 US10836769, Example 55

SMILES FC(F)c1cc(NC(=O)c2c(Cl)c(C(=O)C(=O)NC3(CC(F)(F)C3)c3c[nH]nn3)n3CCCc23)ccc1F

InChI Key InChIKey=XUKFGZBCMOUSTL-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 473069   

TargetCapsid protein(HBV-C)
Gilead Sciences

US Patent
LigandPNGBDBM473069(US10836769, Example 55)
Affinity DataEC50:  3nMAssay Description:A HepG2 cell line overexpressing the HBV virus attachment receptor sodium-taurocholate cotransporting polypeptide (NTCP) was grown to confluency in D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/30/2021
Entry Details
Go to US Patent