BDBM47303 US9023354, AD4-10482

SMILES Oc1c(ccc2cccnc12)C(Nc1ccccn1)c1ccccc1Cl

InChI Key InChIKey=RGPCTXYEMALQFR-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 47303   

TargetE3 ubiquitin-protein ligase Mdm2(Human)
TBA

US Patent
LigandPNGBDBM47303(US9023354, AD4-10482)
Affinity DataIC50: 1.80E+4nMT: 2°CAssay Description:The following example describes an assay that measured the ability of compounds to inhibit the binding of p53 to MDM2 using the AlphaScreen assay tec...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2015
Entry Details
Go to US Patent

TargetProtein disulfide-isomerase(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM47303(US9023354, AD4-10482)
Affinity DataIC50: 500nMAssay Description:Inhibition of recombinant human wild-type N-terminal His-tagged PDIA1 expressed in Escherichia coli strain BL21(DE3) using bovine insulin as substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed