BDBM472932 US10836769, Example 2

SMILES Cc1c(C(=O)Nc2ccc(F)c(c2)C#N)c2CCCn2c1C(=O)C(=O)NC1(CC(F)(F)C1)c1nncs1

InChI Key InChIKey=LJZNMOBKWHOOQW-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 472932   

TargetCapsid protein(HBV-C)
Gilead Sciences

US Patent
LigandPNGBDBM472932(US10836769, Example 2)
Affinity DataEC50:  4.80nMAssay Description:A HepG2 cell line overexpressing the HBV virus attachment receptor sodium-taurocholate cotransporting polypeptide (NTCP) was grown to confluency in D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/30/2021
Entry Details
Go to US Patent