BDBM472834 US10836728, Compound (17)

SMILES COc1ccc(CCN2CCC(O)(C(CN(C)C)C2)c2cccc(c2)C(N)=O)cc1

InChI Key InChIKey=QUKOMMFQDDJVSK-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 472834   

TargetMu-type opioid receptor(Human)
Mebias Discovery

US Patent
LigandPNGBDBM472834(US10836728, Compound (17))
Affinity DataEC50:  467nMAssay Description:G-protein signaling was measured via second messenger cAMP modulation. Detection of cAMP modulation was accomplished in the PathHunter human OPRM1 (&...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/30/2021
Entry Details
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TargetBeta-arrestin-1(Human)
Mebias Discovery

US Patent
LigandPNGBDBM472834(US10836728, Compound (17))
Affinity DataEC50: >1.00E+5nMAssay Description:The DISCOVERX PATHHUNTER β-Arrestin assay is used to measure β-arrestin-2 activity. The technology is based on Enzyme Fragment Complementat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/30/2021
Entry Details
Go to US Patent