BDBM472831 US10836728, Compound (11)

SMILES CN(C)CC1CN(Cc2ccsc2)CCC1(O)c1cccc(c1)C(N)=O

InChI Key InChIKey=PNYVZWBVNNINPD-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 472831   

TargetMu-type opioid receptor(Human)
Mebias Discovery

US Patent
LigandPNGBDBM472831(US10836728, Compound (11))
Affinity DataEC50:  550nMAssay Description:G-protein signaling was measured via second messenger cAMP modulation. Detection of cAMP modulation was accomplished in the PathHunter human OPRM1 (&...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/30/2021
Entry Details
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TargetBeta-arrestin-1(Human)
Mebias Discovery

US Patent
LigandPNGBDBM472831(US10836728, Compound (11))
Affinity DataEC50:  1.07E+4nMAssay Description:The DISCOVERX PATHHUNTER β-Arrestin assay is used to measure β-arrestin-2 activity. The technology is based on Enzyme Fragment Complementat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/30/2021
Entry Details
Go to US Patent