BDBM472819 US10829496, Example 23

SMILES CC[C@H]1[C@@H](COc2csc3cc(C(N)=O)c(OC(C)C)nc23)NC(=O)[C@H]1F

InChI Key InChIKey=GEWAWLWMBOMUII-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 472819   

TargetInterleukin-1 receptor-associated kinase 4(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM472819(US10829496, Example 23)
Affinity DataIC50: 1.40nMAssay Description:The assays were performed in U-bottom 384-well plates. The final assay volume was 30 μL prepared from 15 μL additions of enzyme and substra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/28/2021
Entry Details
Go to US Patent