BDBM472704 3-(1-(2-Chloro-4-fluorobenzyl)-3-((dimethylamino)methyl)-4-hydroxypiperidin-4-yl)benzamide::US10836728, Compound (6)

SMILES CN(C)CC1CN(Cc2ccc(F)cc2Cl)CCC1(O)c1cccc(c1)C(N)=O

InChI Key InChIKey=BUMYFXVLLSFRND-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 472704   

TargetMu-type opioid receptor(Human)
Mebias Discovery

US Patent
LigandPNGBDBM472704(3-(1-(2-Chloro-4-fluorobenzyl)-3-((dimethylamino)m...)
Affinity DataEC50:  102nMAssay Description:G-protein signaling was measured via second messenger cAMP modulation. Detection of cAMP modulation was accomplished in the PathHunter human OPRM1 (&...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/30/2021
Entry Details
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TargetBeta-arrestin-1(Human)
Mebias Discovery

US Patent
LigandPNGBDBM472704(3-(1-(2-Chloro-4-fluorobenzyl)-3-((dimethylamino)m...)
Affinity DataEC50:  2.56E+3nMAssay Description:The DISCOVERX PATHHUNTER β-Arrestin assay is used to measure β-arrestin-2 activity. The technology is based on Enzyme Fragment Complementat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/30/2021
Entry Details
Go to US Patent