BDBM472676 US10836720, HIJ-1016

SMILES NC(=N)NCCCCNC(=O)NC[C@H](NC(=O)[C@@H]1CCCN1S(=O)(=O)c1ccccc1)C(O)=O

InChI Key InChIKey=IUFCIFVCEOUHLU-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 472676   

TargetIntegrin alpha-V/beta-1(Human)
University of California

US Patent
LigandPNGBDBM472676(US10836720, HIJ-1016)
Affinity DataIC50: 100nMAssay Description:The blockade of integrin alpha 5 beta 1 provides a novel target for the treatment of asthma. As shown in FIGS. 1A and 1B, delivery of ATN-161, a low ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/30/2021
Entry Details
Go to US Patent

TargetIntegrin alpha-V/beta-1(Human)
University of California

US Patent
LigandPNGBDBM472676(US10836720, HIJ-1016)
Affinity DataIC50: 5.05E+3nMAssay Description:The blockade of integrin alpha 5 beta 1 provides a novel target for the treatment of asthma. As shown in FIGS. 1A and 1B, delivery of ATN-161, a low ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/30/2021
Entry Details
Go to US Patent

TargetIntegrin alpha-5/beta-1(Human)
University of California San Francisco

Curated by ChEMBL
LigandPNGBDBM472676(US10836720, HIJ-1016)
Affinity DataIC50: 9.70E+3nMAssay Description:Inhibition of alpha5beta1 integrin in human SW480 cells assessed as inhibition of cell adhesion to fibronectin incubated for 60 mins by crystal viole...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetIntegrin alpha-V/beta-1(Human)
University of California

US Patent
LigandPNGBDBM472676(US10836720, HIJ-1016)
Affinity DataIC50: 4nMAssay Description:Inhibition of alphavbeta1 integrin (unknown origin) expressed in CHO cells assessed as inhibition of cell adhesion to fibronectin incubated for 60 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetIntegrin alpha-V/beta-3(Human)
University of California San Francisco

Curated by ChEMBL
LigandPNGBDBM472676(US10836720, HIJ-1016)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of alphavbeta3 integrin (unknown origin) expressed in human SW480 cells transfected with human beta3 assessed as inhibition of cell adhesi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed