BDBM472271 1-(3-cyanobenzyl)-N-(4-(ethylsulfonyl)benzyl)-2-(trifluoromethyl)-1H-::US10829481, Compound I-90

SMILES CCS(=O)(=O)c1ccc(CNC(=O)c2ccc3n(Cc4cccc(c4)C#N)c(nc3c2)C(F)(F)F)cc1

InChI Key InChIKey=ZCLLGTIHAOOKDY-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 472271   

TargetNuclear receptor ROR-gamma(Human)
Vitae Pharmaceuticals

US Patent
LigandPNGBDBM472271(1-(3-cyanobenzyl)-N-(4-(ethylsulfonyl)benzyl)-2-(t...)
Affinity DataKi: <100nMAssay Description:Compounds described herein were tested for ability to bind to RORγ in a cell-free competition assay with commercially available radio-ligand (RL...More data for this Ligand-Target Pair
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Date in BDB:
6/28/2021
Entry Details
US Patent