BDBM472121 CIS-1-(Cyclobutyl-methyl)-8-dimethylamino-3-[[1-(2-hydroxy-ethyl)-1H- [1,2,3]triazol-4-yl]-methyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one::US10829480, Example SC_2160

SMILES CN(C)[C@]1(CC[C@]2(CN(Cc3cn(CCO)nn3)C(=O)N2CC2CCC2)CC1)c1ccccc1

InChI Key InChIKey=VBLSOCKFYRCTFP-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 472121   

TargetMu-type opioid receptor(Human)
Gruenenthal

US Patent
LigandPNGBDBM472121(US10829480, Example SC_2160 | CIS-1-(Cyclobutyl-me...)
Affinity DataKi:  4nMAssay Description:Mu-Opioid Peptide (hMOP): The hMOP receptor binding assay was performed as homogeneous SPA-assay (scintillation proximity assay) using the assay buff...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/28/2021
Entry Details
Go to US Patent

TargetNociceptin receptor(Human)
Gruenenthal

US Patent
LigandPNGBDBM472121(US10829480, Example SC_2160 | CIS-1-(Cyclobutyl-me...)
Affinity DataKi:  39nMAssay Description:The hNOP receptor binding assay was performed as homogeneous SPA-assay (scintillation proximity assay) using the assay buffer 50 mM TRIS-HCl. 10 mM M...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/28/2021
Entry Details
Go to US Patent