BDBM472096 CIS-2-[[1-(Cyclobutyl-methyl)-8-dimethylamino-2-oxo-8-phenyl-1,3- diazaspiro[4.5]decan-3-yl]-methyl]-benzonitrile::US10829480, Example SC_2092

SMILES CN(C)[C@]1(CC[C@]2(CN(Cc3ccccc3C#N)C(=O)N2CC2CCC2)CC1)c1ccccc1

InChI Key InChIKey=COXCTWQMLFTBNV-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 472096   

TargetMu-type opioid receptor(Human)
Gruenenthal

US Patent
LigandPNGBDBM472096(US10829480, Example SC_2092 | CIS-2-[[1-(Cyclobuty...)
Affinity DataKi:  5.60nMAssay Description:Mu-Opioid Peptide (hMOP): The hMOP receptor binding assay was performed as homogeneous SPA-assay (scintillation proximity assay) using the assay buff...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/28/2021
Entry Details
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TargetNociceptin receptor(Human)
Gruenenthal

US Patent
LigandPNGBDBM472096(US10829480, Example SC_2092 | CIS-2-[[1-(Cyclobuty...)
Affinity DataKi:  380nMAssay Description:The hNOP receptor binding assay was performed as homogeneous SPA-assay (scintillation proximity assay) using the assay buffer 50 mM TRIS-HCl. 10 mM M...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/28/2021
Entry Details
Go to US Patent