BDBM472065 CIS-8-Dimethylamino-1-(3-methoxy-3-methyl-butyl)-3-[(4-methoxyphenyl)- methyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one::US10829480, Example SC_2108

SMILES COc1ccc(CN2C[C@]3(CC[C@@](CC3)(N(C)C)c3ccccc3)N(CCC(C)(C)OC)C2=O)cc1

InChI Key InChIKey=GABIRMYMQDJWCZ-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 472065   

TargetMu-type opioid receptor(Human)
Gruenenthal

US Patent
LigandPNGBDBM472065(US10829480, Example SC_2108 | CIS-8-Dimethylamino-...)
Affinity DataKi:  10.1nMAssay Description:Mu-Opioid Peptide (hMOP): The hMOP receptor binding assay was performed as homogeneous SPA-assay (scintillation proximity assay) using the assay buff...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/28/2021
Entry Details
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TargetNociceptin receptor(Human)
Gruenenthal

US Patent
LigandPNGBDBM472065(US10829480, Example SC_2108 | CIS-8-Dimethylamino-...)
Affinity DataKi:  195nMAssay Description:The hNOP receptor binding assay was performed as homogeneous SPA-assay (scintillation proximity assay) using the assay buffer 50 mM TRIS-HCl. 10 mM M...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/28/2021
Entry Details
Go to US Patent