BDBM472060 CIS-3-[[1-[(5-Cyano-2-methoxy-phenyl)-methyl]-8-dimethylamino-2-oxo-8-phenyl- 1,3-diazaspiro[4.5]decan-3-yl]-methyl]-4-methoxy-benzonitrile::US10829480, Example SC_2106

SMILES COc1ccc(cc1CN1C[C@]2(CC[C@@](CC2)(N(C)C)c2ccccc2)N(Cc2cc(ccc2OC)C#N)C1=O)C#N

InChI Key InChIKey=CZQIMPJTMOJZOC-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 472060   

TargetMu-type opioid receptor(Human)
Gruenenthal

US Patent
LigandPNGBDBM472060(US10829480, Example SC_2106 | CIS-3-[[1-[(5-Cyano-...)
Affinity DataKi:  16.5nMAssay Description:Mu-Opioid Peptide (hMOP): The hMOP receptor binding assay was performed as homogeneous SPA-assay (scintillation proximity assay) using the assay buff...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/28/2021
Entry Details
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TargetNociceptin receptor(Human)
Gruenenthal

US Patent
LigandPNGBDBM472060(US10829480, Example SC_2106 | CIS-3-[[1-[(5-Cyano-...)
Affinity DataKi:  1.54E+3nMAssay Description:The hNOP receptor binding assay was performed as homogeneous SPA-assay (scintillation proximity assay) using the assay buffer 50 mM TRIS-HCl. 10 mM M...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/28/2021
Entry Details
Go to US Patent