BDBM472034 CIS-1-(Cyclobutyl-methyl)-8-methylamino-8-phenyl-3-(pyridin-3-yl-methyl)-1,3- diazaspiro[4.5]decan-2-one::US10829480, Example SC_2031

SMILES CN[C@]1(CC[C@]2(CN(Cc3cccnc3)C(=O)N2CC2CCC2)CC1)c1ccccc1

InChI Key InChIKey=PASRXRDOVAGJNP-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 472034   

TargetMu-type opioid receptor(Human)
Gruenenthal

US Patent
LigandPNGBDBM472034(US10829480, Example SC_2031 | CIS-1-(Cyclobutyl-me...)
Affinity DataKi:  4.60nMAssay Description:Mu-Opioid Peptide (hMOP): The hMOP receptor binding assay was performed as homogeneous SPA-assay (scintillation proximity assay) using the assay buff...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/28/2021
Entry Details
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TargetNociceptin receptor(Human)
Gruenenthal

US Patent
LigandPNGBDBM472034(US10829480, Example SC_2031 | CIS-1-(Cyclobutyl-me...)
Affinity DataKi:  140nMAssay Description:The hNOP receptor binding assay was performed as homogeneous SPA-assay (scintillation proximity assay) using the assay buffer 50 mM TRIS-HCl. 10 mM M...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/28/2021
Entry Details
Go to US Patent