BDBM471768 N4-[(2,2-Dimethyl-4H-5-pyrido[1,4]oxazin-3-one)-6-yl]-5-fluoro-N2-[3-(methylaminocarbonylmethyleneoxy)phenyl]-2,4-pyrimidinediamine::US10828301, Compound R940347

SMILES CNC(=O)COc1cccc(Nc2ncc(F)c(Nc3ccc4OC(C)(C)C(=O)Nc4n3)n2)c1

InChI Key InChIKey=HUBYSAWKJWNBMA-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 471768   

TargetTyrosine-protein kinase SYK(Human)
Rigel Pharmceuticals

US Patent
LigandPNGBDBM471768(US10828301, Compound R940347 | N4-[(2,2-Dimethyl-4...)
Affinity DataIC50: 34.5nMAssay Description:Several 2,4-pyrimidinediamine compounds were tested for the ability to inhibit Syk kinase catalyzed phosphorylation of a peptide substrate in a bioch...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/28/2021
Entry Details
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