BDBM471748 5-Fluoro-N4-(3-hydroxyphenyl)-N2-[4-methyl-3-[(N-methylamino)carbonylmethyleneoxy]phenyl]-2,4-pyrimidinediamine::US10828301, Compound R926757

SMILES CNC(=O)COc1cc(Nc2ncc(F)c(Nc3cccc(O)c3)n2)ccc1C

InChI Key InChIKey=YUBHSNYKUZTORO-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 471748   

TargetTyrosine-protein kinase SYK(Human)
Rigel Pharmceuticals

US Patent
LigandPNGBDBM471748(US10828301, Compound R926757 | 5-Fluoro-N4-(3-hydr...)
Affinity DataIC50: 510nMAssay Description:Several 2,4-pyrimidinediamine compounds were tested for the ability to inhibit Syk kinase catalyzed phosphorylation of a peptide substrate in a bioch...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/28/2021
Entry Details
Go to US Patent