BDBM471727 N4-(3,5-Dimethyl-4-hydroxyphenyl)-5-fluoro-N2-[3-[2-(N-morpholino)ethyleneoxy]phenyl]-2,4-pyrimidinediamine::US10828301, Compound R940255

SMILES Cc1cc(Nc2nc(Nc3cccc(O\C=C\N4CCOCC4)c3)ncc2F)cc(C)c1O

InChI Key InChIKey=CPGZBXFGMYFFBC-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 471727   

TargetTyrosine-protein kinase SYK(Human)
Rigel Pharmceuticals

US Patent
LigandPNGBDBM471727(US10828301, Compound R940255 | N4-(3,5-Dimethyl-4-...)
Affinity DataIC50: 770nMAssay Description:Several 2,4-pyrimidinediamine compounds were tested for the ability to inhibit Syk kinase catalyzed phosphorylation of a peptide substrate in a bioch...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/28/2021
Entry Details
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