BDBM471726 N2-[3-(1-Bis(N-methylaminocarbonyl)ethoxy)phenyl]-5-fluoro-N4-(4-isopropoxyphenyl)-2,4-pyrimidineamine::US10828301, Compound R935196

SMILES CNC(=O)C(COc1cccc(Nc2ncc(F)c(Nc3ccc(OC(C)C)cc3)n2)c1)C(=O)NC

InChI Key InChIKey=NKJHONRBRKVTOE-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 471726   

TargetTyrosine-protein kinase SYK(Human)
Rigel Pharmceuticals

US Patent
LigandPNGBDBM471726(US10828301, Compound R935196 | N2-[3-(1-Bis(N-meth...)
Affinity DataIC50: 266nMAssay Description:Several 2,4-pyrimidinediamine compounds were tested for the ability to inhibit Syk kinase catalyzed phosphorylation of a peptide substrate in a bioch...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/28/2021
Entry Details
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