BDBM47165 US8957103, C1::US9364459, I

SMILES COc1cc(cc(OC)c1OC)C1=C(C(=O)NC1=O)c1cn(CCCO)c2ccccc12

InChI Key InChIKey=IFUKBECSYNPLCY-UHFFFAOYSA-N

Data  9 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 47165   

TargetVascular endothelial growth factor receptor 2(Human)
Johannes Gutenberg—Universitat Mainz

US Patent
LigandPNGBDBM47165(US8957103, C1 | US9364459, I)
Affinity DataIC50: 920nMAssay Description:The effect of test compounds on the activity of the protein kinases GSK-3β, VEGFR-2 and FLT-3 was evaluated based on half maximal inhibitory con...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/15/2015
Entry Details
Go to US Patent

TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Johannes Gutenberg—Universitat Mainz

US Patent
LigandPNGBDBM47165(US8957103, C1 | US9364459, I)
Affinity DataIC50: 556nMAssay Description:The effect of test compounds on the activity of the protein kinases GSK-3β, VEGFR-2 and FLT-3 was evaluated based on half maximal inhibitory con...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/15/2015
Entry Details
Go to US Patent

TargetGlycogen synthase kinase-3 beta(Human)
Johannes Gutenberg—Universitat Mainz

US Patent
LigandPNGBDBM47165(US8957103, C1 | US9364459, I)
Affinity DataIC50: 2.25E+3nMAssay Description:The effect of test compounds on the activity of the protein kinases GSK-3β, VEGFR-2 and FLT-3 was evaluated based on half maximal inhibitory con...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/15/2015
Entry Details
Go to US Patent

TargetVascular endothelial growth factor receptor 2(Human)
Johannes Gutenberg—Universitat Mainz

US Patent
LigandPNGBDBM47165(US8957103, C1 | US9364459, I)
Affinity DataIC50: 153nMAssay Description:The effect of test compounds on the activity of the protein kinases GSK-3β, VEGFR-2 and FLT-3 was evaluated based on half maximal inhibitory con...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/15/2015
Entry Details
Go to US Patent

TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Johannes Gutenberg—Universitat Mainz

US Patent
LigandPNGBDBM47165(US8957103, C1 | US9364459, I)
Affinity DataIC50: 554nMAssay Description:The effect of test compounds on the activity of the protein kinases GSK-3β, VEGFR-2 and FLT-3 was evaluated based on half maximal inhibitory con...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/15/2015
Entry Details
Go to US Patent

TargetGlycogen synthase kinase-3 beta(Human)
Johannes Gutenberg—Universitat Mainz

US Patent
LigandPNGBDBM47165(US8957103, C1 | US9364459, I)
Affinity DataIC50: 3.39E+3nMAssay Description:The effect of test compounds on the activity of the protein kinases GSK-3β, VEGFR-2 and FLT-3 was evaluated based on half maximal inhibitory con...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/15/2015
Entry Details
Go to US Patent

TargetVascular endothelial growth factor receptor 2(Human)
Johannes Gutenberg—Universitat Mainz

US Patent
LigandPNGBDBM47165(US8957103, C1 | US9364459, I)
Affinity DataIC50: 920nMAssay Description:The effect of test compounds on the activity of the protein kinases GSK-3β, VEGFR-2 and FLT-3 was evaluated based on half maximal inhibitory con...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2017
Entry Details
Go to US Patent

TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Johannes Gutenberg—Universitat Mainz

US Patent
LigandPNGBDBM47165(US8957103, C1 | US9364459, I)
Affinity DataIC50: 556nMAssay Description:The effect of test compounds on the activity of the protein kinases GSK-3β, VEGFR-2 and FLT-3 was evaluated based on half maximal inhibitory con...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2017
Entry Details
Go to US Patent

TargetGlycogen synthase kinase-3 beta(Human)
Johannes Gutenberg—Universitat Mainz

US Patent
LigandPNGBDBM47165(US8957103, C1 | US9364459, I)
Affinity DataIC50: 2nMAssay Description:The effect of test compounds on the activity of the protein kinases GSK-3β, VEGFR-2 and FLT-3 was evaluated based on half maximal inhibitory con...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2017
Entry Details
Go to US Patent