BDBM471599 US10822334, Compound 11

SMILES CN1CCC(Oc2cccc3ncnc(Nc4ccc(Oc5ccn6ccnc6c5)c(C)c4)c23)C(F)C1

InChI Key InChIKey=PQHWOPVEQRGKDE-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 471599   

TargetReceptor tyrosine-protein kinase erbB-2(Human)
TBA

US Patent
LigandPNGBDBM471599(US10822334, Compound 11)
Affinity DataIC50: 13.1nMAssay Description:HER2: The compounds' inhibition of target modulation were determined as follows: BT474 cells were sorted in 96 well plates (20000 cells/well) wit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2021
Entry Details
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TargetEpidermal growth factor receptor(Human)
TBA

US Patent
LigandPNGBDBM471599(US10822334, Compound 11)
Affinity DataIC50: 3.00E+3nMAssay Description:EGFR: The compounds' inhibition of target modulation were determined as follows: NCI-H838 cells were sorted in 96 well plates (20000 cells/well) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2021
Entry Details
Go to US Patent