BDBM470295 US10815206, Compound I-78

SMILES CN1c2cc(ccc2OC[C@H](NC(=O)C2=NC(Cc3cccc(F)c3)N=N2)C1=O)C#CC(C)(C)O

InChI Key InChIKey=WBZFDSDEAIBFBT-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 470295   

TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
Rigel Pharmaceuticals

US Patent
LigandPNGBDBM470295(US10815206, Compound I-78)
Affinity DataIC50: 33.4nMAssay Description:A 500 ml stock volume of 5× Reaction Kinase Buffer was made by mixing 1000 μl of 1M MgCl2, 500 μl of 1M Tris-HCL pH7.4, 0.5 mg/ml (25 mg) o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2021
Entry Details
US Patent