BDBM469875 CIS-2-[1-(Cyclobutyl-methyl)-8-dimethylamino-2-oxo-8-phenyl-1,3- diazaspiro[4.5]decan-3-yl]-N-(o-tolyl-methyl)-acetamide::US10807989, Example SC_1103

SMILES CN(C)[C@]1(CC[C@]2(CN(CC(=O)NCc3ccccc3C)C(=O)N2CC2CCC2)CC1)c1ccccc1

InChI Key InChIKey=BGOWFMWWNQHJSN-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 469875   

TargetNociceptin receptor(Human)
GrÜNenthal

US Patent
LigandPNGBDBM469875(US10807989, Example SC_1103 | CIS-2-[1-(Cyclobutyl...)
Affinity DataKi:  0.400nMAssay Description:The hNOP receptor binding assay was performed as homogeneous SPA-assay (scintillation proximity assay) using the assay buffer 50 mM TRIS-HCl, 10 mM M...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2021
Entry Details
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TargetMu-type opioid receptor(Human)
GrÜNenthal

US Patent
LigandPNGBDBM469875(US10807989, Example SC_1103 | CIS-2-[1-(Cyclobutyl...)
Affinity DataKi:  7.20nMAssay Description:The hMOP receptor binding assay was performed as homogeneous SPA-assay (scintillation proximity assay) using the assay buffer 50 mM TRIS-HCl (pH 7.4)...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2021
Entry Details
Go to US Patent