BDBM469316 US10807985, Compound 91

SMILES Cn1cc(cn1)-c1cc2c(ncnn2c1)N1CCN(CC1)c1ncc(cn1)[C@](C)(O)c1c(F)cccc1F

InChI Key InChIKey=MKRLXBDUSJQDTA-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 469316   

TargetMast/stem cell growth factor receptor Kit [D816V](Human)
Blueprint Medicines

US Patent
LigandPNGBDBM469316(US10807985, Compound 91)
Affinity DataIC50: 1nMAssay Description:In each well of a 384-well plate, 0.04 ng/ul (0.5 nM) of D816V KIT (Carna Bioscience 08-156) was incubated in a total of 12.5 ul of buffer (100 mM HE...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2021
Entry Details
US Patent