BDBM469171 N-[2-cyclopropyl-7-(1,5-dimethyl-6-oxopyridin- 3-yl)-1,3-benzoxazol-5-yl]propane-2-sulfonamide::US10807982, Example 51

SMILES CC(C)S(=O)(=O)Nc1cc(-c2cc(C)c(=O)n(C)c2)c2oc(nc2c1)C1CC1

InChI Key InChIKey=ASJMQONOWHRNLT-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 469171   

TargetBromodomain-containing protein 4(Human)
Celgene Quanticel Research

US Patent
LigandPNGBDBM469171(N-[2-cyclopropyl-7-(1,5-dimethyl-6-oxopyridin- 3-y...)
Affinity DataIC50: 500nMAssay Description:Determination of the IC50 for the heterocyclic derivative BRD4 inhibitors disclosed herein was performed as follows. His-tagged BREM was cloned, expr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2021
Entry Details
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